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KMID : 0942820090080010072
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Journal of Korean Brain Tumor Society
2009 Volume.8 No. 1 p.72 ~ p.75
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Primary Central Nervous System Lymphoma of T-cell Origin
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Chong Sang-joon
Gwak Ho-Shin
Min Hye-Sook
Yun Tak
Yoo Heon
Shin Sang-Hoon
Lee Seung-Hoon
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Abstract
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Primary central nervous system lymphomas(PCNSLs) are uncommon intracranial tumors and almost of them are known to be of B-cell lineage. PCNSLs of T-cell lineage should be differentiated from that of B-cell lineage with reactive T-cell infiltrations. We report a 62-year-old female presented with gait disturbance and slurred speech. Brain magnetic resonance imaging showed multilobulated homogenous enhancing mass with peritumoral edema in left basal ganglia. With the assistance of detecting T-cell receptor gamma gene rearrangement by polymerase chain reaction, it was diagnosed as PCNSL of T-cell lineage pathologically.
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KEYWORD
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Central nervous system, Lymphoma, T-cell receptor gamma genes, Polymerase chain reaction
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